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Mubritinib CAS 366017-09-6 Mubritinib TAK 165

Place of Origin:Shandong,China (Mainland)
Brand:MOSINTER
Formula:C25H23F3N4O2
Mol. mass:468.47 g/mol
Boiling point:620.9°C at 760 mmHg

  • 366017-09-6
  • MOSINTER
  • 366017-09-6
Product Description

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Supply Capacity

Payment Terms:

T/T, WU

Production Capacity:

1000kg/year

Min. Order:

1 Gram

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according to the customer's requirements 

Means of Transport:

Ocean, Air, Land

Delivery Date:

7 days

 

Mubritinib

CAS 366017-09-6

Mubritinib (TAK-165)  is a potent Neu (HER2) and Cdc2 p34 inhibitor with IC50 of 6 nM and 0.2μM, respectively. TAK 165

alsoinhibits p33cdk2 and p33cdk5. TAK 165 displays > 4000-fold selectivity over EGFR, FGFR, PDGFR, JAK1 and Src.

TAK 165 exhibits potent antiproliferative effects in Neu-overexpressing cancer cell lines (IC50 = 5 nM in BT474 breast

cancer cells) and significantly inhibits bladder, breast and prostate cancer xenograft growth.

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MOSINTER GROUP was established in 2004. The main office is located in Ningbo, China. The production are located in Zhejiang Province, Jiangsu Province and Shandong Province in China. Specializing in the production and marketing of chemical products, MOSINTER GROUP has excellent production equipment and a high-performing sales team as well as advanced manufacturing technique, comprehensive quality management system and modernized testing methods.

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