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Topotecan Hydrochloride CAS 119413-54-6 TPT TOPOTECAN MONOHYDROCHLORIDE

Place of Origin:Shandong,China (Mainland)
Brand:MOSINTER
Molecular formula:C23H23N3O5 •HCl
Molecular weight:457.9 g/mol
Density:1.49g/cm3
Melting Point:213-21℃
  • 119413-54-6

  • MOSINTER

  • 119413-54-6

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Supply Capacity

Payment Terms:

T/T, WU

Production Capacity:

1000kg/year

Min. Order:

1 Gram

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according to the customer's requirements 

Means of Transport:

Ocean, Air, Land

Delivery Date:

7 days

 

Topotecan Hydrochloride

CAS 119413-54-6

Topotecan hydrochloride can inhibit the activity of topoisomerase I, which is needed for DNA replication. After intravenous injection, the product is hydrolyzed in blood and excreted in urine. This product has a rapid serum clearance rate of 62L per hour, widely distributed in the body, with a half-life of about 2-3H. The preclinical test showed that the product had antitumor activity for all kinds of tumors. In phase I clinical trial, the product also has obvious antitumor effect on cisplatin resistant ovarian cancer patients.

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