  0086-18989305995        sales@mosinterchem.com
You are here: Home / Products-list / Pharmaceutical Chemicals API / Antineoplastic Drugs API / Doramapimod CAS 285983-48-4 Doramapimod DoraMapin BIBR796

PRODUCTS DETAILS

Doramapimod CAS 285983-48-4 Doramapimod DoraMapin BIBR796

Place of Origin:Shandong,China (Mainland)
Brand:MOSINTER
Molecular formula:C31H37N5O3
Molecular weight:527.66

  • 285983-48-4
  • MOSINTER
  • 285983-48-4
Product Description


Payment & Shipping Terms

Supply Capacity

Payment Terms:

T/T, WU

Production Capacity:

1000kg/year

Min. Order:

1 Gram

Packing:

according to the customer's requirements 

Means of Transport:

Ocean, Air, Land

Delivery Date:

7 days

 

Doramapimod

CAS 285983-48-4

It is a pyrazole-based allosteric inhibitor of p38 MAP Kinase with a Kd of 0.1 nM. BIRB796 has slow binding kinetics, as evidenced by an marked increase in apparent IC50 after preincubation periods up to 2h, as well as dissociation rates of up to six orders of magnitude greater when compared to other MAPK inhibitors. BIRB796 possesses an excellent selectivity profile over a panel of relevant kinases, with the most active being inhibition of JNK2a2 at 100 nM (330-fold selectivity).Related studies have shown that BIRB796 also inhibits activity and activation of SAPK3/p38g (3% remaining activity at 10 uM). At these concentrations, BIRB796 blocks stress-induced phosphorylation of scaffold protein SAP97.

We can customize according to customer's requirement

if you have any question pls mail us or call us.


PRODUCT INQUIRY
If you would like to have a question then get in touch today, we are ready to assist 24/7.
We welcome your cooperation and we will develop with you.
Factory-direct Connectivity Solutions.
High quality, Competitive Price.
Custom-tailored solutions.
Problem-solving approach.

OUR PRODUCT/SERVICE

MOSINTER GROUP was established in 2004. The main office is located in Ningbo, China. The production are located in Zhejiang Province, Jiangsu Province and Shandong Province in China. Specializing in the production and marketing of chemical products, MOSINTER GROUP has excellent production equipment and a high-performing sales team as well as advanced manufacturing technique, comprehensive quality management system and modernized testing methods.

QUICK LINK

CONTACT INFO

  0086-18989305995
 0086-574-88212215
  sales@mosinterchem.com
  YinXianDaDao 1357, Guangbo Center Office 2003, Ningbo, Zhejiang, China
 forwardcy
 0086-18989305995
 0086-18989305995
Copyright  2020 Mosinter Group Limited All rights reserved.