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Anatrazole is a powerful selective triazole aromatase inhibitor. It can inhibit the aromatase dependent on cytochrome P-450 and block the biosynthesis of estrogen, which is the main chemical Book factor to stimulate the growth of breast cancer cells. The IC50 value of this product to human placenta aromatase was 15 nmol / L. Letrozole is suitable for postmenopausal advanced breast cancer. It is mainly used for second-line treatment after failure of anti estrogen treatment
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