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10-Hydroxycamptothecin CAS 64439-81-2 Hydroxy camptothecine

Place of Origin:Shandong,China (Mainland)
Brand:MOSINTER
Molecular Formula: C20H24N2O6
Specification:CP/USP/EP
Appearance:Yellow crystalline powder
Melting Point:230-237°C
Molecular Weight:388.42

  • 64439-81-2
  • MOSINTER
  • 64439-81-2
Product Description

Payment & Shipping Terms

Supply Capacity

Payment Terms:

T/T, WU

Production Capacity:

1000kg/year

Min. Order:

1 Gram

Packing:

according to the customer's requirements 

Means of Transport:

Ocean, Air, Land

Delivery Date:

7 days

 

10-Hydroxycamptothecin

CAS 64439-81-2

Exemestane is an irreversible steroidal aromatase inhibitors, has similar structure with  its substrate,natural androstenedione. And it is the pseudo substrate of aromatase . The inhibition of aromatase to estrogen deprivation is  a effective method in the treatment of postmenopausal women with hormone dependent breast cancer.

Due to the estrogen of postmenopausal women is mainly produced by androgen (adrenal cortex) ,which transform in the aromatase of peripheral tissues. Exemestane inactivates estrogen by combine with the active site of aromatase irreversibly, then the level of estrogen significantly reduces in blood circulating. 

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