Place of Origin: Zhejiang,China (Mainland)
Molecular formula: C17H12Br2O3
Molecular Weight: 424.08
CAS NO.: 3562-84-3
Risk Codes: R22:Harmful if swallowed
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R22:Harmful if swallowed.;
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Benzbromarone (INN) is a uricosuric agent and non-competitive inhibitor of xanthine oxidase used in the treatment of gout, especially when allopurinol, a first-line treatment, fails or produces intolerable adverse effects. It is structurally related to the antiarrhythmic amiodarone.
1, to any of the ingredients in this product allergy.
2, moderate to severe renal utility (glomerular filtration rate lower than 20ml/min) and patients with kidney stones.
3, pregnant women, pregnant women and lactating women disabled.
1 persistent diarrhea should be discontinued.
2 can not be taken in the acute attack of gout, because the beginning of the treatment phase, with the tissue in the acid digestion, it may aggravate the disease.
3 in order to avoid the early treatment of acute episode of gout, suggestions combined with colchicine or anti-inflammatory medicine in the initial administration.
4 during the treatment, a large number of drinking water in order to increase the amount of urine (early treatment of drinking water volume of not less than 1.5-2 liters), so as not to be excreted in the urine uric acid caused by excessive uric acid crystallization. Regular measurement of urine pH value, in order to promote the alkalinization of urine, as appropriate, given sodium bicarbonate or citric acid mixture, and pay attention to acid-base balance, urine pH should be regulated in 6.2 to 6.8.
5 at the beginning of treatment, a large number of uric acid excreted with urine, so at this time, the dosage should be small (starting dose).
6 long-term medication, should be regularly checked liver function.
7 should avoid the use of medicine for other liver damage.