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Vitamin K is necessary for the liver to synthesize four coagulation factors (active coagulation factor Ⅱ (prothrombin), coagulation factor Ⅶ, coagulation factor Ⅺ and coagulation factor Ⅹ). If vitamin K1 is lacking, the above four coagulation factors synthesized by the liver As abnormal protein molecules, their ability to catalyze blood clotting is greatly reduced. It is known that vitamin K is a cofactor for the carboxylation of glutamate gamma. Without vitamin K, the γ-carboxylation of the above coagulation factors cannot be carried out. In addition, these coagulation factors in the blood are reduced, and coagulation delay and bleeding disorders will occur. In addition, it is recognized that vitamin K is dissolved in the lipids of the mitochondrial membrane and plays an electron transfer role. Vitamin K can increase intestinal peristalsis and secretion. When vitamin K is lacking, smooth muscle tension and contraction are weakened. It can also affect the metabolism of some hormones.
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