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Tazobactam acid CAS 89786-04-9 cl298741 TAZOBACTAM
Chemical Properties: White or off-white powder
Definition: ChEBI: A member of the class of penicillanic acids that is sulbactam in which one of the exocyclic methyl hydrogens is replaced by a 1,2,3-triazol-1-yl group; used (in the form of its sodium salt) in combination with ceftolozane sulfate for treatment of complicat d intra-abdominal infections and complicated urinary tract infections.
Raw materials: Etanol-->Potassium permanganate-->Sodium azide-->Potassium iodide-->Celite -->Ammonium acetate-->Peroxyacetic acid-->Vinyl acetate-->Potassium bromide-->3-Amino-5-mercapto-1,2,4-triazole-->Sulbactam-->phenylhydrazone-->Tazobactam sodium
Tazobactam is a pharmaceutical drug that inhibits the action of bacterial β-lactamases, especially those belonging to the SHV-1 and TEM groups. It is commonly used as its sodium salt, tazobactam sodium.
Tazobactam is combined with the extended spectrum β-lactam antibiotic piperacillin in the drug piperacillin/tazobactam, used in infections duePseudomonas aeruginosa. Tazobactam broadens the spectrum of piperacillin by making it effective against organisms that express β-lactamase and would normally degrade piperacillin.
Tazobactam is a heavily modified penicillin and a sulfone.
Tazobactam was patented in 1982 and came into medical use in 1992.
Category: Other Chemical Products