TICAGRELOR CAS 274693-27-5 Unii-glh0314rvc Ticagrelor(AR-C 126532XX

Model: MOS4
Place of Origin: Zhejiang,China (Mainland)
CAS: 274693-27-5
Molecular Formula: C23H28F2N6O4S
Molecular Weight: 522.574
Content: 98%min
Density: 1.67
Synonyms 1: Azd 6140
Synonyms 2: Unii-glh0314rvc
Synonyms 3: Ticagrelor(AR-C 126532XX


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Payment Terms:L/C, T/T, WUProduction Capacity:300kg/year
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TICAGRELOR CAS 274693-27-5

icagrelor is a new kind of antiplatelet aggregation drug

Medical uses

Ticagrelor is used for the prevention of thrombotic events (for example stroke or heart attack) in people with acute coronary syndrome or myocardial infarction with ST elevation. The drug is combined with acetylsalicylic acid unless the latter is contraindicated. There is no high quality evidence for the use of ticagrelor in non-ST elevation acute coronary syndrome.The FDA indication for ticagrelor is reduction of the rate of cardiovascular death, myocardial infarction (MI), and stroke in people with acute coronary syndrome or history of myocardial infarction.[citation needed]

AHA/ACC Guidelines (09/2014) state: "It is reasonable to choose ticagrelor over clopidogrel for P2Y12 inhibition treatment in patients with NSTE-ACS treated with early invasive strategy and/or coronary stenting".

Ticagrelor was found to be comparable to acetylsalicylic acid in people with acute ischemic stroke or transient ischemic attack.

Ticagrelor is a nucleoside analogue: the cyclopentane ring is similar to the sugar ribose, and the nitrogen rich aromatic ring system resembles the nucleobase purine, giving the molecule an overall similarity to adenosine. The substance has low solubility and low permeability under the Biopharmaceutics Classification System.


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Category: Heart And Cerebral Vessels API

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