has bactericidal, fungicidal and anti-itching effect with the
bactericidal effect being 1/3 of the phenol and also a low irritating
and corrosive property. At low concentration, it can play the role
promoting the regeneration of horny while having keratin exfoliation
effect at high concentration. It is mainly used for rubber adhesives,
plastics, synthetic resins, synthetic fibers, dyes, preservatives,
anti-itch, anti-fungal agent, analytical reagent and can also be used to
treat ringworm, eczema, seborrheic dermatitis, acne and psoriasis.
The chemical property of resorcinol is active and it can participate in the following four kinds of reaction.
(1) It can have reaction with sodium amalgam, water for production of dihydro-resorcinol (1, 3-cyclohexanedione).
(2) It can generate ester with reaction with acid anhydride.
(3) It can react with hydroxylamine in a diketone type to generate oxime.
(4) In the action of concentrated sulfuric acid or zinc chloride, it can
react with phthalic anhydride to generate fluorescent dye-fluorescent
In a concentration of 1% to 2%, it has antiseptic,
bactericidal, fungicidal, astringent, antipruritic and horny promoting
effect. At a concentration between 5% and 20%, it has keratolytic effect
and can cause the exfoliation of stratum corneum. At a concentration of
40%, it has corrosive effect. It can be absorbed through the skin or
It can be used for the treatment of seborrheic
dermatitis, acne, superficial skin fungal infections, tinea versicolor,
calluses, corns, and common warts.
it can cause contact dermatitis and has weak irritation effect on skin
and mucous membrane. This product, when being absorbed through broken
skin and wound surface in the large amount, can lead to myxedema.
2, because this product can be absorbed through the skin or ulcers, and
thus is not suitable or being applied to nfants and young children in
high concentration and large-scale.
3, poisoning symptoms include diarrhea, nausea, vomiting, stomach pain,
dizziness, severe or persistent headache, fatigue or weakness, being
prone to excitement or irritability, sleepiness, sweating, bradycardia,
and shortness of breath.
4, applying this product to the wound of children can lead to methaemoglobinaemia.
5, since this product has anti-thyroid effects, systemic effects is
similar as phenol poisoning, but often accompanied with convulsions.
it can turn pale hair to black color; it can cause skin redness and
scaling at a few days after treatment; take this drug with caution.
2, dark-skinned patients may be caused by its stimulation of pigment generation.
3, when being used in combination with soaps, cleansers, acne
preparations, preparations containing alcohol or acid-dimensional A, it
can cause skin irritation or excessive drying effect.
4, it has anti-thyroid effects; it can lead to myxedema upon long term use (especially used in ulcer surface).
5. This product is toxic and thus this product can't subject to systemic
or long-term use; avoid applying it to the broken skin wound in order
to preventing poisoning.
ways for determination of resorcinol include spectrophotometry,
fluorescence kinetics, high performance liquid chromatography, and
capillary electrophoresis method.
1. It can be used as the raw materials for the
production of synthetic resins, adhesives, dyes and ultraviolet
absorbing agent. It can also be used as the dipped cord of tire.
Medically it can be used as the disinfection antiseptic agent.
2. Resorcinol is also known as 1, 3-hydroquinone. In the field of
pesticides, it can be used as the intermediate 3-chloro-4-methyl
coumarin and herbicide oxyfluorfen in the synthesis of pesticides
coumaphos. It can also be used for the production of dyes, specialty
coatings, pharmaceuticals, photographic material, synthetic resins,
adhesives, and cosmetics.
3. Resorcinol is mainly used for the field of rubber adhesives,
synthetic resins, dyes, preservative, pharmaceutical and analytical
reagents. Resorcinol is similar with phenol and cresol. It can generate
condensation polymer through the reaction with formaldehyde. It can be
used for making glue silk and the adhesive agent of tire cord for
nylon-purpose, making wood glue, and being as the adhesive for vinyl
material and metal. Resorcinol is the intermediate of many kinds of azo
dyes and fur dyes as well as the raw material of pharmaceutical
intermediates, p-nitrogen salicylic acid. Resorcinol has bactericidal
effects and can be used as preservatives for being supplied to cosmetics
and dermatological medicine pastes and ointments. The resorcinol
derivatives, β-methylumbelliferone can be used as the intermediate for
optical bleach; tri-nitro resorcinol is detonator. There is also a
considerable amount of resorcinol being used in the production of
benzophenone-class ultraviolet absorbers. This product can irritate the
skin and mucous membranes, can cause poisoning disease through the rapid
absorption by the skin. Minimum lethal dose of rat being subject to
subcutaneous injection is 450mg / kg.
4. It can be applied to the fields of photographic film, medicines, dyes and chemical fiber industry.
5. It can also be used as reagents for analysis.
6. It can be used for characterization and determination of zinc, lead,
tartaric acid, nitrate and nitrite through colorimetric method; it can
also applied to the colorimetric reaction for measuring sugar and
Furfuryl alcohol; as the reagent for detecting ketone sugars and lignin;
it can also applied to the salt reagent of diazonium compound as well
as to organic synthesis.
Benzene sulfonic acid is sulfonated with oleum; further go through
neutralization, alkaline melting, acidification, n-butanol extraction,
evaporation of the solvent, and distillation to obtain the finished
products. 2. It can be produced through the hydrogenation of
m-dinitrobenzene into m-phenylenediamine which is further subject to
hydrolysis to get the finished product. 3. It can be produced from the
hydrolysis of m-aminophenol. Resorcinol can also derived from benzene
and propylene using peroxide di-isopropylbenzene method with the process
being similar as isopropylbenzene production.
Put benzene, 65% fuming sulfuric acid and sodium sulfate separately into
the reactor; control the reaction temperature at 75 ℃ to obtain the
sulphonate. Then add anhydrous sodium sulfate to this sulphonate, stir
and heat to 175 ℃ for dissolving it; Add sulfur trioxide at this
temperature and continue the reaction for an additional 1.5h to generate
di-sulphonate (with the content of benzene disulfonic acid being 75%).
Use dilute alkali to neutralize the di-sulphonate and remove the excess
amount of sulfate salt; the resulting sodium benzene di-sulfonate is
gradually added into the molten sodium hydroxide 290 °C; raise the
temperature to 325 °C within 15min and further dissolve the alkali
melting substance in water; acidify it with sulfuric acid and extract
with ether; evaporate the solvent to obtain the finished resorcinol
Inhalation of vapors or dust causes irritation of
respiratory tract. Ingestion causes burns of mucous membranes, severe
diarrhea, pallor, sweating, weakness, headache, dizziness, tinnitus,
shock, and severe convulsions; may also cause siderosis of the spleen
and tubular injury to the kidney. Contact with eyes causes irritation.
Can be absorbed from wounds or through unbroken skin, producing severe
dermatitis, methemoglobinemia, cyanosis, convulsions, tachycardia,
dyspnea, and death.
|Content of resorcinol(HPLC)%||≥99.7||99.8|
|Content of hydroquinone(HPLC)%||≤0.05||0.005|
|Content of phenol(HPLC)%||≤0.1||ND|
|Content of pyrocatechol(HPLC)%||≤0.1||ND|