|Payment & Shipping Terms||Supply Capacity|
|Payment Terms:||L/C, T/T, WU||Production Capacity:||33T/Year|
|Min. Order:||10 Kilogram||Packing:||According to the...|
|Means of Transport:||Ocean, Air, Land||Delivery Date:||within 7 days|
Nisoldipine (CAS: 63675-72-9)
Yellow crystalline powder
Nisoldipine (INN) is a calcium channel blocker of the dihydropyridine class. It sold in the United Statesunder the proprietary name Sular. Nisoldipine has tropism for cardiac blood vessels.
Mielcarek J, Grobelny P, Szamburska O (2005). "The effect of beta-carotene on the photostability of nisoldipine.". Methods Find Exp Clin Pharmacol 27 (3): 167–71. doi:10.1358/mf.2005.27.3.890873.PMID 15834448.
Missan S, Zhabyeyev P, Dyachok O, Jones SE, McDonald TF (November 2003). "Block of cardiac delayed-rectifier and inward-rectifier K+ currents by nisoldipine". Br. J. Pharmacol. 140 (5): 863–70.doi:10.1038/sj.bjp.0705518. PMC 1574108. PMID 14530219.
Hamilton S, Houle L, Thadani U (1999). "Rapid-release and coat-core formulations of nisoldipine in treatment of hypertension, angina, and heart failure.". Heart Dis 1 (5): 279–88. PMID 1172063
The product is made of two hydrogen pyridine class calcium antagonists can prevent myocardial and vascular smooth muscle of calcium intake, selective dilating coronary artery and peripheral vascular function, improve the myocardial blood flow, reduce the peripheral resistance, reducing myocardial oxygen consumption, enhance myocardial hypoxia tolerance, reduce high blood pressure patients blood pressure.
Antihypertensive effect was dose dependent. The fall in blood pressure at the same time, the breath and does not affect the central nervous system.
Treatment of mild and moderate hypertension
Usage and dosage: Oral medication, the adult 5-10 mg each time, 2 times a day, once in the morning and night
Adverse reactions: Sometimes a mild, transient palpitations, red face, dizziness, tinnitus, fatigue, nausea, rashes, etc.
Forbidden disease: Pregnant women Allergies are prohibited
The driver, the work high above the antihypertensive treatment, and precision instrument operators should not use this product.
Excessive lowering of blood pressure, severe liver function is impaired and elderly patients should be careful.
Withdrawal should be gradually reduced.
Lactating women such as taking, should first stop breastfeeding
Category: Circulatory System Drugs API