Meglumine CAS 6284-40-8 Methylglucamin Methylglucamine N-Methyl-D-glucamine

Model: MOSINTER
Place of Origin: Zhejiang,China (Mainland)
CAS: 6284-40-8
Assay: ≥99.0%
Appearance: White crystalline powder
BRAND: MOSINTER
Melting point: 128.4℃~130.2℃
Heavy Metals: ≤10ppm
Nickcl: ≤5ppm
Package: 25KG drum

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Product Description

Payment & Shipping Terms Supply Capacity
Payment Terms:L/C, WU, T/TProduction Capacity:2000KG/YEAR
Min. Order:1 KilogramPacking:As per request of...
Means of Transport:Land, Ocean, AirDelivery Date:within 7 days

N-Methyl-D-glucamine (CAS: 6284-40-8)


ITEM

SPECIFICATION

INDEX

Appearance

White to faintly yellowish-white odorless crystals or powder

White crystalline powder

Identification

The mixture turns bright yellow and becomes clear

Complies

Melting point

128℃ ~ 132℃

128.5~129.5℃

Clarity and color of the solution

The solution is clear

Complies

Loss on drying

≤ 1%

0.01%

Residue on ignition 

≤ 0.1%

0.04%

Heavy metals

≤ 20 ppm

Complies

Specific rotation

-15.7° ~ -17.3°

-16.4°

Reducing substances

Conform to the requirement

Complies

Absorbance

≤ 0.03 (20 w/w)

0.003

Residual solvents (CH3OH)

≤ 3000 ppm

150 ppm

Assay

99% ~ 100.5%

99.5%


ITEM

STANDARD

RESULT

Appearance

White crystalline powder

 White crystalline powder

Melting point

128℃~132℃

 128.4℃~130.2℃

Residue On Ignition

≤0.1%

0.03%

Loss On Drying

≤0.5%

0.26%

Assay

≥99.0%

 99.34%

Specific rotation

-15.5°~ -17.5°

 -16.40°

Heavy Metals

≤10ppm

Accords with the specification

Absence of reducing substances

Blue don't change to red

Accords with the specification

Clarity of the solution

Clear and colourless solution

Accords with the specification

Ultraviolet obsorbancy degree

≤0.03

0.01

Readily carbonizable substance

No deeper than the orange red no.2

Accords with the specification

Nickcl

≤5ppm

3ppm


GENERAL DESCRIPTION AND APPLICATIONS

Glucamine, 1-amino-1-deoxy-D-sorbitol, is an amine formed by reduction of glucosylamine or  glucose oxime. N-alkylated glucamines are prepared from D-glucose and relevant alkylamines. Meglumine is N-methyl glucamine, a derivative of sorbitol in which the hydroxyl group in position 1 is replaced by a methylamino group. It is a white crystalline powder; melting at 130 C. Meglumine is used in the preparation of certain radiopaque media such as diatrizoate meglumine and iodipamide meglumine. Meglumine is combined as an excipient (an inert substance) not an active ingredient. Excipients are added to ensure that the shelf-life of the active ingredients can be long enough to be active until internal use. Excipients are combined also to support the active ingredients, so that the latter can be easily administered or absorbed in the body. Examples of meglumine-combined drugs are flunixin meglumine (non-steroidal anti-inflammatory drugs, used as a veterinary anti-inflammatory and analgesic) and meglumine antimoniate (antiprotozoal to treat leishmaniasis). Meglumine is used in ion-exchange resins to chelate boron ions selectively. N-alkyl glucamines are used in preparing functional surfactants and some solutions which are stable over a wide range of pH and ionic strength.


HANDLING AND STORAGE 

Handling:

Provide appropriate exhaust ventilation at places where dust is formed. Normal measures for preventive fire 

protection. 


Storage :

Keep container tightly closed in a dry and well-ventilated place.  

Keep in a dry place.

Category: Diagnostic Agents API

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