|Payment & Shipping Terms ||Supply Capacity |
|Payment Terms:||L/C, T/T, WU||Production Capacity:||100Ton/year|
|Min. Order:||50 Kilogram||Packing:||As per request of...|
|Means of Transport:||Ocean, Air, Land||Delivery Date:||within 7 days|
Enramycin (CAS: 12772-37-1; 11115-82-5)
Gray or beige powder, Have a special foul-smelling
HPLC: The main peak retention time a sample solution and standard solution main peak retention time should be consistent
Min.100% pass through 850um
Min.70% pass through 180um
Loss on drying, %
Heavy metals, ppm
As the standard of 90.0~110.0
Enramycin or Enduracidin is a polypeptide antibiotic produced by Streptomyces fungicidus. Enramycin is widely used as a feed additive for pigs and chickens to prevent necrotic enteritis induced by Gram-positive gut pathogens.
Mechanism of action
Enramycin acts as an inhibitor of the enzyme, MurG, which is essential for cell wall biosynthesis in Gram-positive bacteria. MurG catalyzes the transglycosylation reaction in the last step of peptidoglycan biosynthesis. Inhibiting this step greatly compromises cell wall integrity leading to cell lysis.
Spectrum of susceptibility
Enramycin has been found to be very effective against Gram-positive gut pathogens, most notably, Clostridium perfringens; a leading cause of necrotic enteritis. The following represents MIC data for a couple of veterinary pathogens.
Clostridium perfringens: 0.05 μg/ml – 1.6 μg/ml
Staphylococcus aureus: 0.013 μg/ml – 0.413 μg/ml
Standard grade enramycin is composed of two main components called enramycin A and enramycin B. These two components are routinely used as analytical reference standards; however, their activity as individual compounds does not appear to be widely studied or characterized.
Appearance: Gray or beige powder, Have a special foul-smelling
Package: 25KG Drum or As per request of clients
Category: Veterinary Medicine API
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