Ethylstilbestrol is a synthetic non-steroidal estrogen, which can inhibit the secretion of gonadotropin in the pituitary gland, thus altering the hormone balance in the body and destroying the growth and development conditions of tumor tissue.
1. Supplementary estrogen deficiency in the body, such as atrophic vaginitis, female gonadal dysplasia, menopausal syndrome, senile vaginal dryness and vaginitis, ovariectomy, primary ovarian deficiency.
2. breast cancer, postmenopausal and male advanced breast cancer, who can not be operated on.
3. prostate cancer can not be treated with advanced surgery.
4. prevent postpartum lactation.
A white or almost white, crystalline powder;
practically insoluble in water, freely soluble in alcohol. It dissolves in solutions of the alkali hydroxides.
A. Ultraviolet Absorption. Absorptivities at
230 to 350nm do not differ by more than 3.0%.
B.The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the standard preparation, as obtained in the assay.
Acidity or alkalinity
A solution of 100 mg in 5 mL of neutralized
70% alcohol is neutral to litmus.
Loss on drying
Not more than 0.5%
Residue on ignition
Not more than 0.05%
calculated on the dried basis
Category: Antineoplastic Drugs API