Cefotaxime sodium CAS 64485 -93 -4 Cefotaxime sodium salt Claforan

Model: MOSINTER
Place of Origin: Zhejiang,China (Mainland)
cas: 64485-93-4

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Product Description

Payment & Shipping Terms Supply Capacity
Payment Terms:L/C, T/T, WUProduction Capacity:50Ton/year
Min. Order:1 KilogramPacking:According to request...
Means of Transport:Ocean, Air, LandDelivery Date:within 7 days

Cefotaxime sodium(CAS: 64485-93-4)

Item

Index

Molecular   Formula

C16H16N5NaO7S2

Molecular weight

477.45

Specification

CP/USP/EP

Appearance

White to light yellow crysal

Melting point

162-163 ℃

Refractive index

61 ° (C=1, H2O)

Solubility in   water

aqueous solutions of pH 4.3-6.2 are stable up to 3   weeks at 2-8 °C.soluble

 

GENERAL DESCRIPTION & APPLICATIONS

Cephalosporin: any of a group of broad-spectrum derived from species of fungi of the genus Cephalosporium  and are related to the penicillins in both structure and mode of action but relatively penicillinase-resistant antibiotics. These antibiotics have low toxicity for the host, considering their broad antibacterial spectrum. They have the active nucleus of beta-lactam ring which results in a variety of antibacterial and pharmacologic characteristics when modified mainly by substitution at 3 and 7 positions. Their antibacterial activities result from the inhibition of mucopeptide synthesis in the cell wall. They are widely used to treat gonorrhea, meningitis, pneumococcal, staphylococcal and streptococcal infections. The cephalosporin class of antibiotics is usually divided into generations by their antimicrobial properties. Three generations of cephalosporins are recognized and the fourth has been grouped. Each newer generation of cephalosporins has broader range of activity against gram-negative organisms but a narrower range of activity against gram-positive organisms than the preceding generation. The newer agents have much longer half-lives resulting in the decrease of dosing frequency. Accordingly, the third-generation cephalosporins can penetrate into tissues well, and thus antibiotic levels are good in various body fluids. Third-generation cephalosporins are more active against gram-negative organisms but less active against gram-positive organisms than second-generation agents; examples are cefoperazone, cefotaxime, ceftriaxone, ceftazidime, ceftizoxime, and moxalactam.

Category: Antibiotic Drugs API

Related Category: Veterinary Medicine API  Diagnostic Agents API  Vitamin Preparation API  Psychotropic Drugs API  Endocrine Drugs API 


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